SINGLE-PARTICLE MASS ANALYSIS OF INTACT RIBOSOMES BY MASS PHOTOMETRY AND ORBITRAP-BASED CHARGE DETECTION MASS SPECTROMETRY

Single-particle mass analysis of intact ribosomes by mass photometry and Orbitrap-based charge detection mass spectrometry

Summary: Standard methods for mass analysis measure ensembles of thousand to millions of molecules.This approach enables analysis of monodisperse recombinant proteins, whereas some heterogeneous protein assemblies GPS Navigation Receiver pose a significant challenge, whereby co-occurring stoichiometries, sub-complexes, and modifications hamper anal

read more

Functions of Teacher and Student Code-Switching in an EFL Classroom and Pedagogical Focus: Observations and Implications

Code-switching (CS), the alternation between two or more languages within a stretch of language, is accepted as a valuable strategy of bilinguals in making linguistic choices for communicative purposes.Following different perspectives, CS can be understood either as an attempt to communicate meanings at the macro level Skin Care (such as identity,

read more

Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

Summary: Heme oxygenase-1 (HO-1) is a cytoprotective enzyme that controls inflammatory responses and redox homeostasis; however, its role during pulmonary tuberculosis (TB) remains unclear.Using freshly resected human TB lung tissue, we examined the role of HO-1 within the cellular and pathological spectrum of TB.Flow cytometry and histopathologica

read more

British Society of Echocardiography guideline for the transthoracic echocardiographic assessment of cardiac amyloidosis

Abstract These guidelines form an update of the BSE guideline protocol for the assessment of restrictive cardiomyopathy (Knight et al.in Echo Res Prac, 2013).Since the original recommendations were conceived in 2013, there has been an exponential rise in the diagnosis of cardiac amyloidosis fuelled by increased clinician awareness, improvements in

read more